Other HA fillers have large amounts of dangling and ineffective internal links. These fillers require more BDDE and can lead to higher incidences of
adverse reactions (such as swelling) and decreased durability in the skin.
Thixofix Technology requires less BDDE as dangling and ineffective links are minimized. This more effective cross linking technology results in a safe, long lasting product.
Because there are many HA based fillers on the market, one may ask, "What makes the Revanesse® product line different?" The answer lies in our unique formula and patented Thixotropic cross-linking technology, which allows a highly viscous gel to be injected easily through a fine gauge needle without causing degradation to the modified HA particles while returning to its viscous state providing a soft smooth feel to the skin once it is injected.
Prollenium's® precisely crafted cross-linking process is designed to maximize the effectiveness of the cross-linked HA chains present in the gel. Links between different HA polymer chains are promoted, while ineffective 'dangling' links and less effective links between portions of the same chain are minimized. This leads to a gel, which derives maximum benefit in terms of mechanical properties and durability, with a minimum amount of BDDE – thus leading to fewer incidences of post injection complications such as swelling.
The osmolality and pH of the gel is balanced to be compatible with the fluid in the skin, neither drawing in or releasing water. This minimizes problems of overfilling or the need for volume correction. As the filler is slowly degraded over time the cross-linked network is loosened and this allows for slow expansion of the gel particles that partly offsets the natural loss in dermal filler volume, maintaining the level of correction.
Optimizing all these properties provides for a dermal filler with superior performance and patient satisfaction.
